[The concept of depression--its historical development]. / Conceptul de depresie--dezvoltare istoricaa.

The authors review the historical development of the concept of "depression" and the terminology used by psychiatrists in the description and limitation of various forms of depression. They bring into relief the contribution brought about by the authors who delineated and classified the syndromes of depression, constituting in this way the historical evolution of the concept of depression.

[Observations on deaths in alcoholism]. / Observatii asupra deceselor în alcoolism.

The present study is an attempt to establish the death rate of alcoholic patients with their various psycho-organic complications. The study was done on cases of alcoholic patients hospitalized in our Clinic over the past three decades. Thus, if the mortality index in 46,591 psychic patients hospitalized between 1959 and 1988 was of 0.36%, in alcoholics (totalling 5,580 of all patients) the mortality index was of 1.97%. An analysis of these figures with the aid of the X-square method showed a p of less than 0.001, indicating a significant difference with a probability of over 99.90% between these two groups of patients.

[Clinico-therapeutic observations in the neuroleptic malignant syndrome]. / Observatii clinico-terapeutice asupra sindromului neuroleptic malign.

The special literature of the last two decades has mentioned repeatedly the occurrence of a "malignant neuroleptic syndrome", a severe, and not too rare complication of therapy with neuroleptic drugs. The authors make an analysis of 17 cases, and discuss the conditions of the development, the symptomatology and the treatment of the malignant neuroleptic syndrome. Due to the fact that the use of neuroleptics has been introduced in other fields of medicine the authors consider that information of physicians of all specialties with regard to this severe complication of neuroleptic therapy is useful.

[Historiographic aspects of the development of psychiatric care in Tîrgu-Mures]. / Aspecte istoriografice ale dezvoltarii asistentei psihiatrice în Tîrgu Mures.

Based on certain data collected from archives and publications, the authors show the evolution of psychic patients' care delivery in Tîrgu-Mures, underlying the beginnings of charity care of the institutions operated during the 13th, 14th and 17th centuries. Social advance and the action of a progressive thinking have prepared the way to a modern medical stand which gradually witnessed the separation of psychiatry into the modern clinic of psychiatry. Along the sequences of this evolution the authors review medical and scientific personalities up to the present-day organization and activity of the clinic of psychiatry with its programme of didactic, research and care activities.